215253-32-0Relevant academic research and scientific papers
Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis
Horita, Yasuhiro,Takii, Takemasa,Chiba, Taku,Kuroishi, Ryuji,Maeda, Yasuhiro,Kurono, Yukihisa,Inagaki, Emi,Nishimura, Kenji,Yamamoto, Yoshifumi,Abe, Chiyoji,Mori, Masami,Onozaki, Kikuo
, p. 6313 - 6316 (2009)
A series of sugar derivatives (1-13) were synthesized and evaluated for antibacterial activity against Mycobacterium tuberculosis (MTB), especially multi-drug resistant (MDR) MTB, and the structure-activity relationships of these compounds were studied. The results showed that the compound OCT313 (2-acetamido-2deoxy-β-d-glucopyranosyl N,N-dimethyldithiocarbamate) (4) exhibited significant in vitro bactericidal activity, and that the dithiocarbamate group at C-1 position of the glucopyranoside ring was requisite for the antibacterial activity.
Mechanism of multivalent carbohydrate-protein interactions studied by EPR spectroscopy
Braun, Patrick,N?gele, Bettina,Wittmann, Valentin,Drescher, Malte
supporting information; scheme or table, p. 8428 - 8431 (2011/10/31)
From a distance: Distance measurements in the nanometer range by means of spin-label electron paramagnetic resonance provide structural evidence for multivalent protein-ligand interactions in solution (see picture; protein subunits: blue/green, ligand: bl
Synthesis of hyperbranched aminopolysaccharides
Kadokawa, Jun-Ichi,Sato, Mitsuru,Karasu, Masa,Tagaya, Hideyuki,Chiba, Koji
, p. 2373 - 2376 (2007/10/03)
Sugar dihydroozaxole monomers with two free hydroxyl groups undergo acid-catalyzed polymerization to hyperbranched aminopolysaccharides [Eq. (a)]. Their molecular weights were determined by the light-scattering method to be between 2.3 x 105 an
