215318-35-7

Basic information

• Product Name: 3'-O-(p,p'-dimethoxytrityl)thymidine 5'-(allyl N,N-diisopropylphosphoramidite)
• Synonyms: 3'-O-(p,p'-dimethoxytrityl)thymidine 5'-(allyl N,N-diisopropylphosphoramidite)
• CAS NO: 215318-35-7
• Molecular Weight: 731.826
• Mol File: 215318-35-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3'-O-(p,p'-dimethoxytrityl)thymidine 5'-(allyl N,N-diisopropylphosphoramidite)(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-(p,p'-dimethoxytrityl)thymidine 5'-(allyl N,N-diisopropylphosphoramidite)(215318-35-7)
• EPA Substance Registry System: 3'-O-(p,p'-dimethoxytrityl)thymidine 5'-(allyl N,N-diisopropylphosphoramidite)(215318-35-7)

Safety Data

• Hazardous Substances Data: 215318-35-7(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 164267-52-1 5'-O-tert-butyldimethylsilyl-3'-O-(4,4'-dimethoxytriphenylmethyl)thymidine 
• 40733-28-6 5'-tert-butyldimethylsilyloxy-2'-deoxythymidine 
• 108554-72-9 (allyloxy)bis(diisopropylamino)phosphine 
• 76054-81-4 3'-O-(4,4'-dimethoxytrityl)thymidine 

Downstream Products

• 215318-36-8 C₆₇H₆₇N₆O₁₆P 

Relevant articles and documents

Evidence supporting the activity of 2'-C-cyano-2'-deoxy-1-β-D-arabino- pentafuranosylcytosine as a terminatorin enzymatic DNA-chain elongation

To investigate the stability of 2'-C-cyano-2'-deoxy- 1-β-D-arabino- pentafuranosylcytosine 3'phosphoric acid, its thymidine ester was prepared via the phosphoramidite method using allyl protection for the phosphate function. This ester is stable under aci

A novel approach to oligodeoxyribonucleotides bearing phosphoric acid esters at the 3'-terminals via the phosphoramidite method with allyl protection: An efficient synthesis of base-labile nucleotide-amino acid and - peptide conjugates

A new method for synthesis of 3'-end-phosphorylated DNA oligomers via the phosphoramidite method with allyl protection has been developed. This method is particularly useful for the preparation of derivatives with base- labile structures such as oligoDNA-OPO(OH)OCH2CH(R)Z, in which Z is an electron-withdrawing function. For example, a oligonucleotide-amino acid conjugate, 5'TGTCGACACCCAATT3'-OPO(OH)OCH2CH(NH2)COOH, and a oligonucleotide-peptide conjugate, 5'TGTCGACACCCAATT3'- OPO(OH)OCH2CH(NH2)CONHCH2COOH, have been obtained in high purity.