215377-86-9Relevant academic research and scientific papers
Adamantanyl-substituted PEPPSI-type palladium(II) N-heterocyclic carbene complexes: synthesis and catalytic application for CH activation of substituted thiophenes
Glushkov, Vladimir A.,Denisov, Michail S.,Gorbunov, Aleksey A.,Myalitzin, Yurii A.,Dmitriev, Maksim V.,Slepukhin, Pavel A.
, p. 217 - 228 (2019/05/15)
[Figure not available: see fulltext.] Starting from 1-adamantanyl-3-imidazole, a number of new 1-adamantanyl-3-benzylimidazolium salts and corresponding unsymmetrically substituted Pd(II) PEPPSI-type complexes were prepared, including dichloride, dibromide, and diiodide. Single crystal X-ray crystallography confirmed solid state structures in six cases. The complexes reported in this work displayed moderate activities as precatalysts for CH activation/arylation reaction of substituted thiophenes.
A general catalyst for the β-selective C - H bond arylation of thiophenes with iodoarenes
Ueda, Kirika,Yanagisawa, Shuichi,Yamaguchi, Junichiro,Itami, Kenichiro
supporting information; experimental part, p. 8946 - 8949 (2011/02/21)
Open access: The normally less-reactive β position of thiophenes was previously inaccessible to direct functionalization. However, the β selectivity observed with the catalytic system PdCl2/P{OCH(CF 3)2}3/Ag2CO3 in the arylation of thiophenes with iodoarenes (see scheme) is a remarkably general phenomenon applicable to unsubstituted, monosubstituted, and disubstituted thiophene derivatives, as well as thiophene-containing fused aromatic compounds.
