215452-46-3Relevant academic research and scientific papers
Heterocyclization of o-(arylethynyl)arylhydrazines as a new procedure for the synthesis of substituted 1H-and 2H-indazoles and indoles
Prikhodko,Vasilevsky
, p. 1268 - 1273 (2007/10/03)
Procedures for the preparation of 3-substituted 1H-and 2H-indazoles and 2-substituted indoles were developed based on cross-coupling of o-iodoarylhydrazines with copper acetylenides in pyridine or dimethylformamide. An alternative procedure for the synthesis of 3-substituted 1H-indazoles involves cyclocondensation of (2-chloroaryl)acetylenes with hydrazine hydrate in butanol.
