215453-84-2

Usage

Uses

Used in Organic Synthesis:
4-(4-Bromophenoxy)tetrahydro-2H-pyran is used as a building block in the synthesis of various organic compounds for [application reason] its unique structure and reactivity.
Used in Pharmaceutical Intermediates:
4-(4-Bromophenoxy)tetrahydro-2H-pyran is used as a pharmaceutical intermediate for [application reason] its potential to be incorporated into the development of new drugs.
Used in Agrochemicals:
4-(4-Bromophenoxy)tetrahydro-2H-pyran is used as a component in agrochemicals for [application reason] its potential applications in this field due to its unique structure.
Used in Materials Science:
4-(4-Bromophenoxy)tetrahydro-2H-pyran is used in materials science for [application reason] its potential to contribute to the development of new materials with specific properties.

Upstream product

• 2081-44-9 Tetrahydro-pyran-4-ol 
• 106-41-2 4-bromo-phenol 
• 60-29-7 diethyl ether 
• 1972-28-7 diethylazodicarboxylate 
• 4143-61-7 diethyl diazodicarboxylate 

Downstream Products

• 215453-85-3 4-(tetrahydro-2H-pyran-4-yloxy)benzenesulfonyl chloride 
• 1416157-80-6 4,4,5,5-tetramethyl-2-(4-((tetrahydro-2H-pyran-4-yl)oxy)phenyl)-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Method of preparing Quinoline-5,8-dione derivatives for TGase 2 inhibitor

I Is -5,8- of the quinoline, dione derivative compound. of Formula I, or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein the compound of Formula, TGase 2 has, inhibitory effects TGase 2, and thus the pharmaceutical composition may be useful for preventing or treating disorders or diseases mediated by TGase 2 or inhibiting. (by machine translation)

Quinoline-5,8-dione derivatives for TGase 2 inhibitor, and the pharmaceutical composition comprising the same

The present invention relates to a quinolin-5,8-dione derivative compound represented by chemical formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula I of the present invention has a TGase 2 inhibitory effect, and the pharmaceutical composition comprising the same can be usefully used for preventing or treating disorders or diseases mediated by TGase 2 or response to TGase 2 inhibition.COPYRIGHT KIPO 2020

COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF

The invention relates to compounds, pharmaceutical compositions and medicaments comprising such compounds, and the use of these compounds, compositions, and medicaments in methods of treating a variety of diseases and disorders.

Base catalyzed Mitsunobu reactions as a tool for the synthesis of aryl sec-alkyl ethers

A facile and versatile method for the synthesis of aryl sec-alkyl ethers from phenols with alcohols in the presence of base via a Mitsunobu reaction is described.

Anilide derivative, production and use thereof

This invention is to provide a compound of the formula: wherein R1is an optionally substituted 5- to 6-membered ring; the ring A is an optionally substituted 6- to 7-membered ring; the ring B is an optionally substituted benzene ring; n is an integer of 1 or 2; Z is a chemical bond or a divalent group; R2is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, (2) an optionally substituted nitrogen-containing heterocyclic ring group which may contain a sulfur atom or an oxygen atom as ring constituting atoms and wherein a nitrogen atom may form a quaternary ammonium, (3) a group binding through a sulfur atom or (4) a group of the formula: ?wherein k is 0 or 1, and when k is 0, a phosphorus atom may form a phosphonium; and R5and R6are independently an optionally substituted hydrocarbon group, an optionally substituted hydroxy group or an optionally substituted amino group, and R5and R6may bind to each other to form a cyclic group together with the adjacent phosphorus atom, or a salt thereof , which is useful for antagonizing CCR5 and also for the prevention and treatment of infectious disease of HIV.

Heterocyclic derivatives and their use as antithrombotic agents

The present invention relates to antithrombotic compounds comprising the group Q, Q having formula (I), wherein the substructure (i) is a structure selected from (a, b and c), wherein X is O or S; X′ being independently CH or N; and m is 0, 1, 2 or 3; wherein the group Q is bound through an oxygen atom or an optionally substituted nitrogen or carbon atom, or a pharmaceutically acceptable salt thereof or a prodrug thereof. The compounds of the invention are therapeutically active and in particular are antithrombotic agents.