215454-23-2

Usage

Type of compound

Isoquinolinol compound

Primary use

Pharmaceutical industry for the synthesis of various drugs and pharmaceutical products

Physical appearance

Yellow to greenish powder

Melting point

234-238°C

Molecular weight

146.17 g/mol

Biological activity

Potential as an anticancer and antitumor agent

Other therapeutic potential

Neurodegenerative diseases and bacterial infections

Importance

Significant chemical compound with potential applications in medicine and drug development

Upstream product

• 42398-75-4 7-methoxy-isoquinolin-1-ylamine 
• 7651-83-4 isoquinolin-7-ol 
• 872087-87-1 5-(tert-butyldimethylsilanyloxy)-isoquinoline 

Relevant academic research and scientific papers

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR

Basic molecular building blocks such as benzene rings, amidines, guanidines, and amino groups have been combined in a systematic way to generate ligand candidates for HIV-1 TAR RNA. Ranking of the resulting compounds was achieved in a fluorimetric Tat-TAR

Heterocyclic derivatives and their use as antithrombotic agents

The present invention relates to antithrombotic compounds comprising the group Q, Q having formula (I), wherein the substructure (i) is a structure selected from (a, b and c), wherein X is O or S; X′ being independently CH or N; and m is 0, 1, 2 or 3; wherein the group Q is bound through an oxygen atom or an optionally substituted nitrogen or carbon atom, or a pharmaceutically acceptable salt thereof or a prodrug thereof. The compounds of the invention are therapeutically active and in particular are antithrombotic agents.