215460-40-5

Usage

Uses

Used in Organic Synthesis:
4-(Tetrahydropyran-4-yloxy)benzaldehyde is used as an intermediate in organic synthesis for the production of various chemicals. Its unique structure allows it to be a versatile building block in the synthesis of complex organic molecules.
Used in Fragrance Industry:
4-(Tetrahydropyran-4-yloxy)benzaldehyde is used as a fragrance component in perfumes and other personal care products. Its strong aromatic smell makes it a valuable addition to the fragrance industry, contributing to the creation of unique and appealing scents.
Used in Chemical Industry:
The tetrahydropyran-4-yloxy group in 4-(Tetrahydropyran-4-yloxy)benzaldehyde provides stability and enhances its solubility in various solvents, making it useful in a wide range of applications in the chemical industry. This includes its use as a starting material for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1/C12H14O3/c13-9-10-1-3-11(4-2-10)15-12-5-7-14-8-6-12/h1-4,9,12H,5-8H2

Upstream product

• 2081-44-9 Tetrahydro-pyran-4-ol 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 864266-61-5 (4-((tetrahydro-2H-pyran-4-yl)oxy)phenyl)methanamine 

Relevant academic research and scientific papers

A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides

Functionalized (hetero)aromatic compounds are indispensable chemicals widely used in basic and applied sciences. Among these, especially aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides represent valuable fine and bulk chemicals, which are used in chemical, pharmaceutical, agrochemical, and material industries. For their synthesis, catalytic aerobic oxidation of alcohols constitutes a green, sustainable, and cost-effective process, which should ideally make use of active and selective 3D metals. Here, we report the preparation of graphitic layers encapsulated in Co-nanoparticles by pyrolysis of cobalt-piperazine-tartaric acid complex on carbon as a most general oxidation catalyst. This unique material allows for the synthesis of simple, functionalized, and structurally diverse (hetero)aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides from alcohols in excellent yields in the presence of air.

3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization

The discovery, synthesis and SAR of a novel series of 3-benzyl-1,3-oxazolidin-2-ones as positive allosteric modulators (PAMs) of mGluR2 is described. Expedient hit-to-lead work on a single HTS hit led to the identification of a ligand-efficient and struct