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CBZ-L-CYCLOPROPYL-ALA-OH, also known as carboxybenzyl-L-cyclopropylalanine, is an unnatural amino acid derivative that plays a significant role in peptide synthesis and research. CBZ-L-CYCLOPROPYL-ALA-OH features a cyclopropyl side chain, which introduces unique steric and electronic properties to peptides and proteins. The carboxybenzyl group serves as a protecting group for amino acids, ensuring controlled reactivity of specific functional groups during the synthesis process. CBZ-L-CYCLOPROPYL-ALA-OH is a valuable building block for designing novel peptides with modified characteristics, making it instrumental for investigating protein folding, binding interactions, and other biochemical phenomena.

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  • 215523-07-2 Structure
  • Basic information

    1. Product Name: CBZ-L-CYCLOPROPYL-ALA-OH
    2. Synonyms: CBZ-L-CYCLOPROPYL-ALA-OH;N-Cbz-(S)-3-cyclopropylalanine
    3. CAS NO:215523-07-2
    4. Molecular Formula: C14H17NO4
    5. Molecular Weight: 263.291
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 215523-07-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: CBZ-L-CYCLOPROPYL-ALA-OH(CAS DataBase Reference)
    10. NIST Chemistry Reference: CBZ-L-CYCLOPROPYL-ALA-OH(215523-07-2)
    11. EPA Substance Registry System: CBZ-L-CYCLOPROPYL-ALA-OH(215523-07-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 215523-07-2(Hazardous Substances Data)

215523-07-2 Usage

Uses

Used in Pharmaceutical Industry:
CBZ-L-CYCLOPROPYL-ALA-OH is used as a key component in the development of novel peptides for various pharmaceutical applications. Its unique properties allow for the creation of peptides with enhanced stability, selectivity, and bioactivity, which can be crucial for drug discovery and therapeutic interventions.
Used in Research and Development:
In the field of research, CBZ-L-CYCLOPROPYL-ALA-OH is utilized as a building block for synthesizing peptides with altered properties. This enables scientists to study protein folding, binding interactions, and other biochemical processes, contributing to a deeper understanding of protein function and the development of new therapeutic strategies.
Used in Peptide Synthesis:
CBZ-L-CYCLOPROPYL-ALA-OH is employed as a crucial component in peptide synthesis, where its cyclopropyl side chain and carboxybenzyl protecting group contribute to the controlled formation of peptide bonds and the synthesis of peptides with specific characteristics. This makes it an essential tool for creating custom peptides for various applications, including drug development, diagnostics, and research.

Check Digit Verification of cas no

The CAS Registry Mumber 215523-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,5,2 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 215523-07:
(8*2)+(7*1)+(6*5)+(5*5)+(4*2)+(3*3)+(2*0)+(1*7)=102
102 % 10 = 2
So 215523-07-2 is a valid CAS Registry Number.

215523-07-2Relevant articles and documents

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS

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Page/Page column 116; 117, (2011/04/14)

Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.

Protease inhibitors

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, (2008/06/13)

The present invention provides bis-aminomethylcarbonyl compounds that are inhibitors of cysteine and serine proteases. The compounds are particularly useful for treating diseases in which excess cysteine protease activity has been implicated, including osteoporosis, periodontitis and arthritis.

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