215585-96-9Relevant academic research and scientific papers
A concise synthesis of natural benzofuran neolignans and analogues
Duan, Xin-Fang,Shen, Gang,Zhang, Zhan-Bin
experimental part, p. 2547 - 2552 (2010/09/08)
The first total synthesis of four naturally occurring benzofuran neolignans and two analogues was achieved in four steps in 44-51% overall yield. Key steps involved a two-step construction of benzofuran nucleus and a Suzuki coupling. This synthesis has been proven straightforward and efficient, and more related analogues can be prepared for structure-activity relationship explorations. Georg Thieme Verlag Stuttgart New York.
XH-14 analogues as adenosine antagonists
Scammells, Peter J.,Baker, Stephen P.,Beauglehole, Anthony R.
, p. 1517 - 1524 (2007/10/03)
Analogues of the potent adenosine antagonist 5-(3'-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzo[b]furan-3-carbaldehyde (XH-14, 1) with alternate substituents in the 2-, 5- and 7-positions have been synthesised. The affinity of these compo
