215600-96-7Relevant academic research and scientific papers
Enantioselective, catalytic trichloromethylation through visible-light-activated photoredox catalysis with a chiral iridium complex
Huo, Haohua,Wang, Chuanyong,Harms, Klaus,Meggers, Eric
supporting information, p. 9551 - 9554 (2015/08/18)
An enantioselective, catalytic trichloromethylation of 2-acyl imidazoles and 2-acylpyridines is reported. Several products are formed with enantiomeric excess of ≥99%. In this system, a chiral iridium complex serves a dual function, as a catalytically active chiral Lewis acid and simultaneously as a precursor for an in situ assembled visible-light-triggered photoredox catalyst.
TETRAHYDROISOQUINOLINE COMPOUND
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Page/Page column 58, (2010/01/29)
The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.
Fused azolium salts XVIII [1]. Synthesis and reactivity of a novel fused heteroaromatic system : [1,2,3]triazolo[1,5-b]isoquinolinium salts
Beres, Mariann,Hajos, Gyoergy,Riedl, Zsuzsanna,Timari, Geza,Messmer, Andras
, p. 897 - 908 (2007/10/03)
Oxidative cyclization of 3-isoquinolyl ketone hydrazones afforded the novel tricyclic heteroaromatic [1,2,3]triazolo[1,5-b]isoquinolinium salts. The reactivity of the ring system towards nucleophiles proved to be regioselective. Secondary amines induced r
