21562-57-2 Usage
Chemical compound
A derivative of prostaglandin, a type of lipid compound that has various physiological effects.
Natural occurrence
Found in the human body and involved in various physiological processes.
Structural features
Contains three hydroxyl groups (-OH) and a ketone functional group (C=O), which contribute to its unique properties and potential biological activities.
Potential use in pharmaceuticals
Studied for its potential in the development of drugs for treating inflammation, pain, and other conditions.
Research value
Its structure and properties make it a valuable compound for further research and potential medical applications.
Biological activities
As a naturally occurring prostaglandin, it is likely to have various biological activities, although specific details are not provided in the material.
Stereochemistry
The compound has specific stereochemistry, with the hydroxyl groups at the 1, 11alpha, and 15S positions, and a trans double bond at the 13E position in the prostaglandin backbone.
Solubility
The solubility of 1,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-9-ONE is not mentioned in the material, but prostaglandins are typically lipid-soluble and can dissolve in organic solvents.
Stability
The stability of 1,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-9-ONE is not discussed in the material, but prostaglandins are generally sensitive to heat, light, and oxidation, which may affect the compound's stability.
Check Digit Verification of cas no
The CAS Registry Mumber 21562-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,5,6 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21562-57:
(7*2)+(6*1)+(5*5)+(4*6)+(3*2)+(2*5)+(1*7)=92
92 % 10 = 2
So 21562-57-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h12-13,16-18,20-22,24H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,20+/m0/s1
21562-57-2Relevant articles and documents
Regio- and Stereoselectivity of the Reaction between Cyanocuprates and Cyclopentene Epoxides. Application to the Total Synthesis of Prostaglandins
Marino, Joseph P.,Pradilla, Roberto F. de la,Laborde, Edgardo
, p. 4898 - 4913 (2007/10/02)
A systematic study of the reaction between cyclopentene epoxides and alkyl-, alkenyl-, and arylcyanocuprates is described.Alkylcyanocuprates react with complete regio- and stereoselectivity to provide trans-4-alkylcyclopent-2-enols in excellent yields.Vin
Stereocontrolled Synthesis of Prostaglandins from Cyclopentadiene Monoepoxide
Marino, Joseph P.,Pradilla, Roberto Fernandez de la,Laborde, Edgardo
, p. 5279 - 5280 (2007/10/02)
Two complementary syntheses of prostaglandins from the same key intermediate 3, available in four steps from cyclopentadiene monoepoxide, are described.In one approach, a saturated α-chain is introduced via a 1,4-addition of an appropriately functionalized cyanocuprate reagent onto silyl enol ether 3.The resulting prostanoid compound was converted into the bronchodilator 1-decarboxy-1-hydroxymethyl PGE1, PGE1, and PGF1α.The second approach involves the transformation of silyl enol ether 3 into the known prostanoid precursor 11 via selective addition of carbethoxycarbene and subsequent fluoride-induced ring opening of the resulting (silyloxy)cyclopropane carboxylate ester.
