215649-01-7

Upstream product

• 544-97-8 dimethyl zinc(II) 
• 215649-00-6 5-phenoxy-(3',5'-dimethoxyphenyl)pent-1-one 
• 588-63-6 3-phenoxypropyl bromide 
• 120078-30-0 2-(3,5-dimethoxyphenyl)-2-methylpropanal 
• 22972-63-0 α,α-dimethyl-3,5-dimethoxyphenylacetonitrile 
• 63985-67-1 (3-phenoxypropyl)triphenylphosphonium bromide 
• 75-24-1 trimethylaluminum 
• 58545-33-8 1-(3,5-dimethoxyphenyl)-5-phenoxypentane 
• 39969-57-8 1-bromo-4-butoxybenzene 
• 19179-31-8 3,5-dimethoxy-benzonitrile 

Downstream Products

• 215649-02-8 5-(6-bromo-2-methylhexan-2-yl)resorcinol 

Relevant academic research and scientific papers

2-CYCLOALKYL RESORCINOL CANNABINERGIC LIGANDS

The present invention relates to novel 2-cycloalkyl resorcinol compounds; to pharmaceutical compositions comprising the compounds; and to methods of preparing the compounds and uses thereof. The disclosed compounds can bind to and modulate the cannabinoid

Access to "friedel-Crafts-Restricted" tert -alkyl aromatics by activation/methylation of tertiary benzylic alcohols

Herein we describe a two-step protocol to prepare m-tert-alkylbenzenes. The appropriate tertiary benzylic alcohols are activated with SOCl2 or concentrated HCl and then treated with trimethylaluminum, affording the desired products in 68-97% yields (22 examples). This reaction sequence is successful in the presence of a variety of functional groups, including acid-sensitive and Lewis-basic groups. In addition to t-Bu groups, 1,1-dimethylpropyl and 1-ethyl-1-methylpropyl groups can also be installed using this method.

WATER-SOLUBLE CANNABINOIDS

Water-soluble cannabinoid compounds that are agonists of CB1 and CB2 cannabinoid receptors are provided. The compounds are made water-soluble by derivatization of the alkyl side chain and/or the phenolic hydroxyl group of tetrahydroc

Potent cyano and carboxamido side-chain analogues of 1',1'-dimethyl- Δ8-tetrahydrocannabinol

The synthesis and pharmacological profile of several cyano (1a-e) and carboxamido (2a-h) side-chain-substituted analogues of 1',1'-dimethyl-Δ8- THC are described. Commercially available cyano compound 3 was transformed to the resorcinol 6 in a

Water soluble derivatives of cannabinoids

Water-soluble esters of tetrahydrocannabinoids, which are well-suited for administration in therapeutic aqueous formulations, having following general formula: STR1 wherein a - - - b designates a 9(10) or a 9(8) double bond, R' is a --(CH2)sub