Cas 215673-79-3,1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester

215673-79-3

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Basic information

Product Name: 1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester
Synonyms: 1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester
CAS NO:215673-79-3
Molecular Formula:
Molecular Weight: 774.784
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester(215673-79-3)
EPA Substance Registry System: 1-Cyclopropyl-6-fluoro-7-{4-[(2S,4S)-4-mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidine-2-carbonyl]-piperazin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 4-nitro-benzyl ester(215673-79-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 215673-79-3(Hazardous Substances Data)

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215673-79-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 215673-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,6,7 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 215673-79:
(8*2)+(7*1)+(6*5)+(5*6)+(4*7)+(3*3)+(2*7)+(1*9)=143
143 % 10 = 3
So 215673-79-3 is a valid CAS Registry Number.

215673-79-3Upstream product

215673-66-8 (3S,5S)-1-(4-nitrobenzyloxycarbonyl)-3-thioacetyl-5-[4-(3-(4-nitrobenzyloxycarbonyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl)-1-piperazinyl]-carbonylpyrrolidine

215673-79-3Downstream Products

215673-79-3Relevant academic research and scientific papers

Preparation and antimicrobial assessment of 2-thioether-linked quinolonyl-carbapenems

Hershberger, Paul M.,Switzer, A. Greg,Yelm, Kenneth E.,Coleman, Milt C.,Devries, Carol A.,Rourke, F. James,Davis, Barb W.,Kraft, William G.,Twinem, Tracy L.,Koenigs, Paula M.,Paule, Suzanne M.,Siehnel, Richard J.,Zoutendam, Paul H.,Imbus, Rebecca,Demuth Jr., Thomas P.

, p. 857 - 871 (1998)

This reports the synthesis and in vitro antimicrobial properties of a series of 2-thioether-linked quinolonyl-carbapenems. Although the title compounds exhibited broad spectrum activity, the MICs were generally higher than those observed for selected benchmark carbapenems, quinolonyl-penems, and quinolones. Enzyme assays suggested that the title compounds are potent inhibitors of penicillin binding proteins and inefficient inhibitors of bacterial DNA-gyrase. Uptake studies indicated that the new compounds are not substrates for the nor A encoded quinolone efflux pump.

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