215713-41-0Relevant academic research and scientific papers
Studies with polyfunctionally substituted heteroaromatics, a new route to synthesis of thiopyrano[3,2-c]pyridine, thiopyrano[4,3-b]pyridine, and bipyridyl derivatives
Abu-Shanab, Fathi A.,Selim, Mohamed R.,Wakefield, Basil J.,Elnagdi, Mohamed H.
, p. 175 - 184 (1997)
Pyridine derivatives (4a, d, e) were reacted with carbon disulfide in dry tetrahydrofurane (THF) in the presence of potassium tert-butoxide under Argon to yield thiopyanopyridine derivatives (7, 10). Also (2a, 4c) were reacted with carbon disullide under the same condition producing the dithioacetal derivatives (13) which were converted to bipyridyl derivatives (14) via reaction with cyanothioacetamide in isopropyl alcohol and sodium isopropoxide.
New method of synthesis of 5-acetyl-3-cyano-6-methylpyridine-2(1H)-thione and its properties
Yakunin,Dyachenko,Litvinov
, p. 581 - 587 (2007/10/03)
5-Acetyl-3-cyano-6-methylpyridine-2(1H)-thione was obtained by the reaction of ethoxymethyleneacetylacetone with cyanothioacetamide in the presence of N-methylmorpholine. Its alkylation, bromination of the 2-methylthio derivative, and the conversions of its 5-bromoacetyl derivative have been studied.
