215719-36-1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 215719-40-7 (1S,4R,5R)-4-Benzoylamino-7-oxo-2,6-diaza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 269730-12-3 (1S,4R,5R)-6-(2,4-Dimethoxy-benzyl)-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-7-oxo-2,6-diaza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 269730-13-4 (1S,4R,5R)-4-Benzoylamino-6-(2,4-dimethoxy-benzyl)-7-oxo-2,6-diaza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 

Downstream Products

• 215719-43-0 methyl {N²-[(benzyloxy)carbonyl]-O⁴-(tert-butyl)-L-aspart-1-yl}-(2S,3R,4R)-4-(benzoylamino)-3-{[(tert-butoxy)carbonyl]amino}prolinate 
• 215719-45-2 tert-butyl (3S,7R,8R,8aS)-7-(benzoylamino)-8-{[(tert-butoxy)carbonyl]amino}octahydro-1,4-dioxopyrrolo[1,2-a]pyrazine-3-acetate 
• 215719-37-2 methyl (2S,3R,4R)-4-(benzoylamino)-1-[(benzyloxy)carbonyl]-3-{[(tert-butoxy)carbonyl]amino}prolinate 
• 215719-47-4 ((3S,7R,8R,8aS)-8-Amino-7-benzoylamino-1,4-dioxo-octahydro-pyrrolo[1,2-a]pyrazin-3-yl)-acetic acid 
• 215719-42-9 methyl (2S,3R,4R)-4-(benzoylamino)-3-{[(tert-butoxy)carbonyl]amino}prolinate 

Relevant academic research and scientific papers

Stabilisation of β-hairpin conformations in a protein surface mimetic using a bicyclic template derived from (2S,3A,4R)-diaminoproline

A trifunctional template, derived by formal coupling of (S)-aspartic acid and (2S,3R,4R)-diaminoproline (available from vitamin C) as a diketopiperazine, was incorporated by solid-phase peptide synthesis into a protein loop mimetic containing the sequence