21572-61-2

Usage

Uses

Used in Medical Applications:
(2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium is used as a potential therapeutic agent for vasodilation and cancer therapy due to its ability to release nitric oxide (NO). (2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium has been investigated for its potential to improve blood flow and target cancer cells, making it a promising candidate for the development of new medical treatments.
Used in Antimicrobial Applications:
(2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium is used as an antimicrobial agent due to its ability to release nitric oxide (NO), which has been shown to have antimicrobial properties. (2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium has been studied for its potential to combat various types of infections and could be a valuable addition to the arsenal of antimicrobial agents.
Used in Anti-inflammatory Applications:
(2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium is used as an anti-inflammatory agent due to its ability to release nitric oxide (NO), which has been shown to have anti-inflammatory effects. (2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium has been studied for its potential to reduce inflammation and could be a promising candidate for the development of new anti-inflammatory treatments.
Used in Scientific Research:
(2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)diazenium is used as a research compound in the scientific community to study the properties and potential applications of diazeniumdiolate compounds. Its ability to release nitric oxide (NO) makes it a valuable tool for investigating the role of NO in various physiological processes and the development of new therapeutic agents.

Upstream product

• 17581-52-1 2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-one hydrazone 
• 77-47-4 hexachlorocyclopentadiene 

Downstream Products

• 5216-71-7 5-Cyclohexyl-tetrachlor-cyclopentadien-(1,3) 
• 6693-51-2 --hydrazin 
• 5216-72-8 Norcaran-7-spiro-5'-(tetrachlor-cyclopenta-1',3'-dien) 
• 10269-62-2 tetrachloro-α-pyrone 
• 4723-74-4 tetrachlorocyclopentadienone 
• 13736-99-7 N,N'-Bis-(2,3,4,5-tetrachloro-cyclopenta-2,4-dienylidene)-hydrazine 
• 114663-28-4 4,4,6,6-tetramethyl-2,2-diphenyl-5-(2,3,4,5-tetrachlorcyclopenta-2,4-dien-1-yliden)-1-thiaspiro<2.3>hexan 
• 17581-52-1 2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-one hydrazone 
• 1807-65-4 α-Diphenylmethylen-β-tetrachlor-cyclopentadienyliden-hydrazin 
• 72749-20-3 trans-bis(triphenylphosphine)(tetrachlorodiazocyclopentadiene)chloroiridium(I)*toluene 

Relevant academic research and scientific papers

The reaction of cyclopentadienylidine, fluorenylidene and tetrachlorocyclopentadienylidene with alcohols. A laser flash photolysis study

Rate constants of reaction of cyclopentadienylidene, fluorenylidene and tetrachlorocyclopentadienylidene with alcohols and other quenchers were determined by laser flash photolysis methods. The rate constants of reaction of cyclopentadienylidene and fluorenylidene with various alcohols were determined and found to increase with increasing alcohol acidity. Alcohols as a group reacted faster with cyclopentadienylidene and fluorenylidene than likely ylide formers such as pyridine, ethyl acetate and tetrahydrofuran. Bronsted plots of the reaction of cyclopentadienylidene and fluorenylidene with alcohols are linear with slopes of 0·061 and 0·082, respectively. In the case of tetrachlorocyclopentadienylidene, an ylide type of reaction mechanism with alcohols is indicated. Tetrachlorocyclopentadienylidene reacts most rapidly with the least acidic alcohol studied and this carbene reacts more rapidly with tetramethylurea, pyridine and tetrahydrofuran than with methanol.

Formation of a 4H-Cyclopenta-1,2,3-thiadiazole by Rearrangement of a Transient N-(Thionitroso)cyclopenta-2,4-diene-1-imine

1-Diazo-2,3,4,5-tetrachlorocyclopenta-2,4-diene, 2, reacts with sulfur dichloride or with disulfur dichloride to form 4,4,5,6-tetrachloro-4H-cyclopenta-1,2,3-thiadiazole, 6, most likely via a transient N-(thionitroso)cyclopenta-2,4-diene-1-imine, 4.

Isolation of an Antiaromatic Singlet Cyclopentadienyl Zwitterion

The reaction of triplet tetrachlorocyclopentadienylidene with BF3 in rare gas matrices yields a zwitterion consisting of a cyclopentadienyl cation bearing a positive charge and a negatively charged BF3 unit. IR and UV-vis spectra as well as the absence of EPR signals demonstrate a singlet ground state of the zwitterion, and its calculated geometry and magnetic properties clearly reveal a strong antiaromatic character. The zwitterion is highly labile and by visible or IR irradiation rearranges via a 1,2-fluorine migration from boron to carbon. Interaction with a second molecule of BF3 stabilizes the zwitterion and suppresses the fluorine migration, thus providing a convenient and efficient synthesis of an antiaromatic molecule under very mild conditions.

Pentachlorocyclopentadienyl derivatives of manganese and rhodium

Reaction of diazotetrachlorocyclopentadiene, I, with di-μ-chloro-bis(1,5-cyclooctadienerhodium), [RhCl(1,5-C8H12)]2, gives high yields of (η5-pentachlorocyclopentadienyl)(1,5-cyclooctadiene)rhodium, Rh(η5-C5Cl5)(COD), II. A similar reaction between I and pentacarbonylchloromanganese, MnCl(CO)5, gave two products: pentacarbonyl(η1-pentachlorocyclopentadienyl)manganese, Mn(η1-C5Cl5)(CO)5, III, and tricarbonyl(η5-pentachlorocyclopentadienyl)manganese, Mn(η5-C5Cl5)(CO)3, IV. III is the first transition metal complex containing a η1-C5Cl5- ring and for which there is no analog in C5H5--Mn chemistry. These compounds and other polychloro-substituted cyclopentadienyl complexes have been characterized by infrared, Raman, 13C nuclear magnetic resonance, and 35Cl nuclear quadrupole resonance spectroscopy. Qualitative results from investigations into the mechanism of the insertion reactions of diazocyclopentadienes into manganese-halogen bonds are discussed.