215788-34-4

Usage

Uses

Used in Pharmaceutical Synthesis:
5-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE is used as a building block in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and properties make it a valuable intermediate in the production of a wide range of chemical substances.
Used in Research and Development:
In the field of research and development, 5-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE is utilized for the investigation of its potential biological and pharmacological activities, contributing to the discovery of new therapeutic agents and understanding of molecular mechanisms.

InChI:InChI=1/C10H10F3N.ClH/c11-10(12,13)9-3-1-2-7-6-14-5-4-8(7)9;/h1-3,14H,4-6H2;1H

Upstream product

• 215794-20-0 2,2,2-trifluoro-1-[5-(trifluoromethyl)-3,4-dihydro Isoquinoline-2(1H)-yl]ethane-1-one 
• 215797-90-3 2,2,2-trifluoro-N-(2-(2-(trifluoromethyl)phenyl)ethyl)acetamide 
• 774-18-5 2-(2-(trifluoromethyl)phenyl)ethan-1-amine 
• 27810-64-6 isoquinoline-5-carboxylic acid 

Downstream Products

• 1028330-57-5 C₃₀H₃₃F₃N₂O 

Relevant academic research and scientific papers

Deoxofluorination of (Hetero)aromatic Acids

Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride. The obtained products were used as starting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines - valuable building blocks for medicinal chemistry and agrochemistry.

Synthesis method of 5-trifluoromethyl isoquinoline-8-formic acid

The invention discloses a synthesis method of 5-trifluoromethyl isoquinoline-8-formic acid. The method comprises the steps of by using 4-trifluoromethyl phenylethylamine as a raw material, carrying out amino protection, cyclization, hydrolysis, brominatio

Synthesis method of 6-(trifluoromethyl) isoquinoline-5-ol

The invention discloses a synthesis method of 6- (trifluoromethyl) isoquinoline-5-ol, which comprises the following steps of by using p-trifluoromethyl phenylethylamine as a raw material, carrying outamino protection, cyclization, hydrolysis, bromination,

TRIAZOLOPHTHALAZINE COMPOUNDS, USE AS ANTI-HUMAN IMMUNODEFICIENCY VIRUS INHIBITORS OF HIV VIF-DEPENDENT DEGRADATION OF APOBEC3

The present disclosure is concerned with triazolophthalazine compounds that are capable of inhibiting infection by the Human Immunodeficiency Virus (HIV) by inhibiting HIV Vif-dependent degradation of the APOBEC3 innate immune system. The present disclosu

TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.