215794-95-9

Upstream product

• 108-24-7 acetic anhydride 
• 215794-85-7 pyrimidin-2-yl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside 
• 16697-49-7 3,4,6-tri-O-benzyl-1,2-O-(methoxyethylidene)-β-D-mannopyranose 

Downstream Products

• 183885-23-6 methyl 2,3,4-tri-O-benzyl-6-O-(2,6-di-O-acetyl-3,4-di-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis and glycosylation of pyrimidin-2-yl 1-thio-α-D-manno- and -α-L-rhamnopyranoside

Pyrimidin-2-yl 2,3,4,6-tetra-O-benzyl-1-thio-α-D-mannopyrano side (9), pyrimidin-2-yl 2,3,4-tri-O-benzyl-α-L-rhamnopyranoside (10), pyrimidin-2-yl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside (7), and pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside (8) were prepared almost quantitatively from the corresponding protected 1,2-O-methoxyethylidene-β-D-manno-or-β-L-rhamnopyranose with 2-mercaptopyrimidine in the presence of mercuric bromide. Coupling reactions of the thioglycosides promoted by silver triflate with suitable glycosyl acceptors afforded 1,2-trans linked disaccharides. Copyright (C) 1998 Elsevier Science Ltd.