2158-71-6

Basic information

• Product Name: 1,4-Benzoquinone, 2-(N,N-bis(2-chloroethyl)amino)-
• Synonyms: 1,4-Benzoquinone, 2-(N,N-bis(2-chloroethyl)amino)-;2-(bis(2-chloroethyl)amino)-1,4-benzoquinone;2-[N,N-Bis(2-chloroethyl)amino]-1,4-benzoquinone
• CAS NO: 2158-71-6
• Molecular Formula: C10H11 Cl2 N O2
• Molecular Weight: 248.11
• Mol File: 2158-71-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 357.5°Cat760mmHg
• Flash Point: 170°C
• Appearance: /
• Density: 1.33g/cm³
• Vapor Pressure: 2.72E-05mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: 1,4-Benzoquinone, 2-(N,N-bis(2-chloroethyl)amino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzoquinone, 2-(N,N-bis(2-chloroethyl)amino)-(2158-71-6)
• EPA Substance Registry System: 1,4-Benzoquinone, 2-(N,N-bis(2-chloroethyl)amino)-(2158-71-6)

Safety Data

• Hazardous Substances Data: 2158-71-6(Hazardous Substances Data)

Usage

Classification

Potent antitumor antibiotic and cancer chemotherapeutic agent

Origin

Derived from the natural product mitomycin

Applications

Treatment of various cancers (stomach, pancreas, bladder, and lung cancers)

Mechanism of Action

Causes DNA cross-linking and inhibits DNA synthesis

Purpose

Prevents cancer cells from dividing and growing

Administration

Often administered intravenously

Known Effects

Potent cytotoxic effects on cancer cells

Importance

Considered an effective tool in the fight against cancer

InChI:InChI=1/C10H11Cl2NO2/c11-3-5-13(6-4-12)9-7-8(14)1-2-10(9)15/h1-2,7H,3-6H2

Upstream product

• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 106-51-4 p-benzoquinone 

Downstream Products

• 15482-85-6 2-[bis-(2-chloro-ethyl)-amino]-5-morpholin-4-yl-[1,4]benzoquinone