21582-50-3Relevant academic research and scientific papers
1-Substituted-1,2-dihydrothieno[2,3-d]-pyrimidin-2-one derivatives
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, (2008/06/13)
1-Substituted-1,2-dihydrothieno[2,3-d]-pyrimidin-2-ones of the formula, STR1 wherein R is lower alkyl or cyclopropylmethyl, R1 is halogen, lower alkyl or nitro, R2 is hydrogen or lower alkyl and R3 is hydrogen or halogen, are obtained by treating a trihaloacetamidothiophene derivative with ammonia. These compounds have excellent pharmacological activities such as uricosuric activity.
Thieno[2,3-d]pyrimidine derivatives
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, (2008/06/13)
Novel thienopyrimidine derivatives which have excellent pharmacological uricosuric activity are prepared by reacting a thiophene derivative with cyanic acid or a salt thereof, urea or a reactive ester of carbamic acid. If desired, alkylated, halogenated o
