215872-03-0

Upstream product

• 208753-51-9 3-Ethyl-5-(toluene-4-sulfonyl)-4-[4-(3-trifluoromethyl-3H-diazirin-3-yl)-phenyl]-1,5-dihydro-pyrrol-2-one 
• 208753-55-3 t-butyl 3-(3-allyloxy-3-oxopropyl)-5-formyl-4-methyl-1H-pyrrole-2-carboxylate 
• 208753-56-4 3-(2-Allyloxycarbonyl-ethyl)-5-[4-ethyl-5-oxo-3-[4-(3-trifluoromethyl-3H-diazirin-3-yl)-phenyl]-1,5-dihydro-pyrrol-(2Z)-ylidenemethyl]-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 

Downstream Products

• 220183-09-5 3-(5-{4-ethyl-5-oxo-3-[4-(3-trifluoromethyl-3H-diazirin-3-yl)-phenyl]-1,5-dihydro-pyrrol-2-ylidenemethyl}-2-formyl-4-methyl-1H-pyrrol-3-yl)-propionic acid allyl ester 

Relevant academic research and scientific papers

An efficient method to construct the A,B-rings component toward total syntheses of phycocyanobilin and its derivative as a photoprobe

Total syntheses of physocyanobilin and its derivative bearing a photoreactive group at the D-ring accomplished by developing a new and efficient method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl or 1- tosylethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one and a 2-formyl pyrrole derivative in the presence of (n)Bu3P and a base, followed by reduction with aluminum amalgam and a subsequent acid or base treatment.

Efficient construction of A,B-rings component for syntheses of phycocyanobilin and its derivative

Total syntheses of phycocyanobilin and its photoactivatable derivative were accomplished by developing a new and versatile method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl) -3