215924-28-0Relevant academic research and scientific papers
Highly enantioselective synthesis of glycidic amides using camphor-derived sulfonium salts. Mechanism and applications in synthesis
Aggarwal, Varinder K.,Charmant, Jonathan P. H.,Fuentes, Daniel,Harvey, Jeremy N.,Hynd, George,Ohara, Diasuke,Picoul, Willy,Robiette, Raphael,Smith, Catherine,Vasse, Jean-Luc,Winn, Caroline L.
, p. 2105 - 2114 (2006)
The reactions of a range of amide-stabilized sulfur ylides derived from readily available camphor-derived sulfonium salts for the synthesis of glycidic amides have been studied. Primary, secondary, and tertiary amides were tested, and it was found that th
ASYMMETRIC SYNTHESIS OF GLYCIDIC AMIDES
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Page/Page column 16-17, (2008/06/13)
Enantiomerically enriched trans-2,3-epoxyamides of the formula (I) in which R1 is a 1-18C aliphatic hydrocarbyl optionally substituted by one or more substituent groups selected from halo, nitro, phenyl and -ORW, where RW
Highly enantioselective Darzens reaction of a camphor-derived sulfonium amide to give glycidic amides and their applications in synthesis
Aggarwal, Varinder K.,Hynd, George,Picoul, Willy,Vasse, Jean-Luc
, p. 9964 - 9965 (2007/10/03)
The reaction of an amide-stabilized sulfonium ylide bearing chiral groups on sulfur has been investigated. We have discovered that the camphor-derived amide-stabilized ylide reacts with aldehydes at -50 °C in ethanol to give glycidic amides in one step wi
