215930-44-2

Upstream product

• 80510-04-9 1,2-bis(phosphino)benzene 
• 215930-49-7 (4R,5S,6S,7R)-5,6-Bis-benzyloxy-4,7-dimethyl-[1,3,2]dioxathiepane 2,2-dioxide 
• 156764-21-5 3,4-di-O-benzyl-1,6-di-O-toluenesulfonyl-D-mannitol 
• 175845-24-6 1,2-bis(phospholano)benzene 
• 215930-48-6 (2R,3R,4R,5R)-3,4-dibenzyloxyhexane-2,5-diol 

Relevant academic research and scientific papers

Asymmetric hydrogenation of β-keto esters

Enantiomerically pure β-hydroxy esters are prepared by a process in which β-keto esters are reacted with hydrogen in the presence of catalysts of the formula LRuX2where X is halogen, acetate, allyl, methallyl, 2-phenylallyl, perchlorate, trifluoroacetate, tetrafluoroborate, hexafluoroantimonate, hexafluorophosphate, hexafluoroarsenate or trichloroacetate, L is a bidentate phospholane of the formula I ?where B=a bridging link with 1-5 carbon atoms between the two phosphorus atoms, R1=H, C1-C6-alkyl, aryl, alkylaryl or SiR23, R2=alkyl or aryl, m=0 or 1, R3=H or OR4, and R4=R1, with the proviso that if m=1 then R3=H and if m=0 then R3≠ H.