21598-27-6

Basic information

• Product Name: Piperazine, 1,4-bis(4-fluorophenyl)-
• CAS NO: 21598-27-6
• Molecular Formula: C16H16F2N2
• Molecular Weight: 274.313
• Mol File: 21598-27-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Piperazine, 1,4-bis(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1,4-bis(4-fluorophenyl)-(21598-27-6)
• EPA Substance Registry System: Piperazine, 1,4-bis(4-fluorophenyl)-(21598-27-6)

Safety Data

• Hazardous Substances Data: 21598-27-6(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 460-00-4 1-Bromo-4-fluorobenzene 

Relevant articles and documents

Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst

A Pd/P(t-Bu), catalyst system has revealed very high activity and selectivity for the amination of N-(hetero)aryl halides with unprotected piperazine. A wide variety of N-(hetero)arylpiperazines could be prepared using this catalyst. Turnover numbers up to 6400mol/mol have been obtained.