2160-63-6

Usage

Uses

Used in Scientific Research:
5-Bromothiophene-2-carboxaldehyde oxime is used as a chemical intermediate for the synthesis of more complex chemical compounds. Its unique structure and reactivity make it a valuable component in the development of new molecules with potential applications in various fields.
Used in Organic Chemistry:
In the field of organic chemistry, 5-Bromothiophene-2-carboxaldehyde oxime is used as a reagent in various chemical reactions. Its organobromine and oxime functionalities allow for a range of reactions, such as coupling and condensation, which can lead to the formation of new compounds with desired properties.
Used in Pharmaceutical Development:
5-Bromothiophene-2-carboxaldehyde oxime may be used as a building block in the design and synthesis of new pharmaceutical compounds. Its unique structure could potentially contribute to the development of novel drugs with improved efficacy and reduced side effects.
Used in Material Science:
In material science, 5-Bromothiophene-2-carboxaldehyde oxime could be used in the synthesis of new materials with specific properties, such as improved conductivity, stability, or reactivity. Its incorporation into polymers or other materials could lead to the development of advanced materials for various applications.
Used in Environmental Applications:
5-Bromothiophene-2-carboxaldehyde oxime may also find use in environmental applications, such as in the development of new methods for pollution control or remediation. Its chemical properties could potentially be harnessed to improve the efficiency of environmental processes or to create new materials for environmental protection.

InChI:InChI=1/C5H4BrNOS/c6-5-2-1-4(9-5)3-7-8/h1-3,8H/b7-3-

Upstream product

• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 

Downstream Products

• 76371-66-9 5-bromo-2-thiophene carboxamide 

Relevant academic research and scientific papers

Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity

A series of phidianidine B derivatives were synthesized by introducing various heterocyclic rings. Their inhibitory effects on PTP1B and other PTPs (TCPTP, SHP1, SHP2 and LAR) were evaluated. A majority of them displayed significant inhibitory potency and specific selectivity over PTP1B. The SAR and molecular docking analysis were also described.

Design of α7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [18F] quinuclidine derivative

In this report, we describe the synthesis of a novel library of α7 nAChR ligands based on the modulation of the quinuclidine, quinazoline and tropane moieties. Spirane derivatives were newly synthesized under stereo specific 1,3 dipolar cylcoadditions. On

A practical and cost-efficient, one-pot conversion of aldehydes into nitriles mediated by 'activated DMSO'

Participation of activated DMSO in the one-pot transformation of aldehydes to nitriles has been described by reacting aldehydes with NHHHCl in DMSO in the absence of any added base or catalyst. The method is applicable to access a wide range of aromatic, heterocyclic, and aliphatic nitriles, in which only water is a byproduct. A straightforward and practical procedure is demonstrated on a multigram scale. Georg Thieme Verlag Stuttgart - New York.

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones of formula (I) and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing such compounds as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid-fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

THIENYL COMPOUNDS

Compounds of formula I : and pharmaceutically-acceptable salts thereof, wherein Ar and R are as defined in the specification, compositions containing such compounds and the use of such compounds and compositions for use in therapy.