Cas 216002-23-2,7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid [(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-amide

216002-23-2

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Basic information

Product Name: 7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid [(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-amide
Synonyms:
CAS NO:216002-23-2
Molecular Formula:
Molecular Weight: 533.473
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid [(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-amide(CAS DataBase Reference)
NIST Chemistry Reference: 7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid [(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-amide(216002-23-2)
EPA Substance Registry System: 7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid [(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-amide(216002-23-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 216002-23-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 216002-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,0,0 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 216002-23:
(8*2)+(7*1)+(6*6)+(5*0)+(4*0)+(3*2)+(2*2)+(1*3)=72
72 % 10 = 2
So 216002-23-2 is a valid CAS Registry Number.

216002-23-2Upstream product

170640-09-2 7,8-dihydro-7-methyl-5-(4-methylphenyl)-8-oxo-1,7-naphthyridine-6-carboxylic acid

216002-23-2Downstream Products

216002-23-2Relevant academic research and scientific papers

Axially chiral N-benzyl-n,7-dimethyl-5-phenyl-1,7-naphthyridine-6- carboxamide derivatives as tachykinin NK1 receptor antagonists: Determination of the absolute stereochemical requirements

Ikeura, Yoshinori,Ishichi, Yuji,Tanaka, Toshimasa,Fujishima, Akira,Murabayashi, Mika,Kawada, Mitsuru,Ishimaru, Takenori,Kamo, Izumi,Doi, Takayuki,Natsugari, Hideaki

, p. 4232 - 4239 (2007/10/03)

A potent and orally active NK1 antagonist, trans-N-[3,5- bis(trifluoromethyl)benzyl]-7,8-dihydro-N,7-dimethyl-5-(4-methylphenyl)-8- oxo-1,7-naphthyridine-6-carboxamide (1t), was shown to exist as a mixture of separable and stable (R)- and (S)-a

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