216013-89-7

Basic information

• Product Name: N-[(R)-3-dodecanoyloxytetradecanoyl]-L-serine benzyl ester
• Synonyms: N-[(R)-3-dodecanoyloxytetradecanoyl]-L-serine benzyl ester
• CAS NO: 216013-89-7
• Molecular Weight: 603.883
• Mol File: 216013-89-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-[(R)-3-dodecanoyloxytetradecanoyl]-L-serine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(R)-3-dodecanoyloxytetradecanoyl]-L-serine benzyl ester(216013-89-7)
• EPA Substance Registry System: N-[(R)-3-dodecanoyloxytetradecanoyl]-L-serine benzyl ester(216013-89-7)

Safety Data

• Hazardous Substances Data: 216013-89-7(Hazardous Substances Data)

Upstream product

• 91681-56-0 (3R)-3-dodecanoyloxytetradecanoic acid 
• 1738-72-3 L-serine benzyl ester 
• 107856-74-6 C₂₆H₅₀O₄ 

Downstream Products

• 216013-93-3 N-[(R)-3-dodecanoyloxytetradecanoyl]-O-[2-deoxy-4-O-diphenylphosphono-3-O-[(R)-3-dodecanoyloxytetradecanoyl]-6-O-(2,2,2-trichloro-1,1-dimethylethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl]-L-serine benzyl ester 

Relevant articles and documents

Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors

Aminoalkyl glucosaminide phosphate (AGP) compounds that are adjuvants and immunoeffectors are described and claimed. The compounds have a 2-deoxy-2-amino glucose in glycosidic linkage with an aminoalkyl (aglycon) group. Compounds are phosphorylated at the 4 or 6 carbon on the glucosaminide ring and comprise three 3-alkanoyloxyalkanoyl residues. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for using the compounds as adjuvants and immunoeffectors are also disclosed.

Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors

Aminoalkyl glucosaminide phosphate (AGP) compounds that are adjuvants and immunoeffectors are described and claimed. The compounds have a 2-deoxy-2-amino glucose in glycosidic linkage with an aminoalkyl (aglycon) group. Compounds are phosphorylated at the 4 or 6 carbon on the glucosaminide ring and comprise three 3-alkanoyloxyalkanoyl residues. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Methods for using the compounds as adjuvants and immunoeffectors are also disclosed.

Synthesis and biological evaluation of a new class of vaccine adjuvants: Aminoalkyl glucosaminide 4-phosphates (AGPs)

A novel series of acylated ω-aminoalkyl 2-amino-2-deoxy-4-phosphono-β- D-glucopyranosides (aminoalkyl glucosaminide 4-phosphates) was synthesized and screened for immunostimulant activity. Several of these compounds enhance the production of tetanus toxoid-specific antibodies in mice and augment vaccine-induced cytotoxic T cells against EG.7-ova target cells.