216097-69-7 Usage
Uses
Used in Pharmaceutical Industry:
8-aMinoisoquinolin-1-ol is used as a therapeutic agent for its antitumor activities, offering potential in cancer treatment. It has been studied for its ability to target and treat various types of cancer, making it a promising candidate for further research and development in oncology.
Used in Organic Synthesis:
8-aMinoisoquinolin-1-ol is used as a key intermediate in the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable building block for the creation of new molecules with potential applications in various fields.
Used in Biological Imaging:
8-aMinoisoquinolin-1-ol is used as a fluorescent probe in biological imaging. Its fluorescent properties allow researchers to visualize and study biological processes at the molecular level, providing valuable insights into cellular mechanisms and functions.
Used in Antioxidant Applications:
8-aMinoisoquinolin-1-ol is used as an antioxidant, helping to protect cells from damage caused by reactive oxygen species. Its antioxidant properties make it a potential candidate for use in the development of treatments for various diseases and conditions associated with oxidative stress.
Check Digit Verification of cas no
The CAS Registry Mumber 216097-69-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,0,9 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 216097-69:
(8*2)+(7*1)+(6*6)+(5*0)+(4*9)+(3*7)+(2*6)+(1*9)=137
137 % 10 = 7
So 216097-69-7 is a valid CAS Registry Number.
216097-69-7Relevant academic research and scientific papers
Thorat, Shivaji A.,Lee, Yoonji,Jung, Aeran,Ann, Jihyae,Ahn, Songyeon,Baek, Jisoo,Zuo, Dongxu,Do, Nayeon,Jeong, Jin Ju,Blumberg, Peter M.,Esch, Timothy E.,Turcios, Noe A.,Pearce, Larry V.,Ha, Hee-Jin,Yoo, Young Dong,Hong, Sunhye,Choi, Sun,Lee, Jeewoo
, p. 370 - 384 (2021)
Among a series of benzopyridone-based scaffolds investigated as human transient receptor potential vanilloid 1 (TRPV1) ligands, two isomeric benzopyridone scaffolds demonstrated a consistent and distinctive functional profile in which 2-oxo-1,2-dihydroquinolin-5-yl analogues (e.g., 2) displayed high affinity and potent antagonism, whereas 1-oxo-1,2-dihydroisoquinolin-5-yl analogues (e.g., 3) showed full agonism with high potency. Our computational models provide insight into the agonist-antagonist boundary of the analogues suggesting that the Arg557 residue in the S4-S5 linker might be important for sensing the agonist binding and transmitting signals. These results provide structural insights into the TRPV1 and the protein-ligand interactions at a molecular level.
