21610-80-0

Upstream product

• 64-17-5 ethanol 
• 5487-33-2 O-benzylhomoisovanillic acid 
• 23428-77-5 1‐(3‐(benzyloxy)‐4‐methoxyphenyl)ethanone 
• 23428-78-6 4-[(3-benzyloxy-4-methoxy-phenyl)-thioacetyl]-morpholine 

Downstream Products

• 115262-58-3 (+/-)-cis-1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 115262-58-3 (+/-)-trans-1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 115262-42-5 1-(3-benzyloxy-4-methoxyphenethyl)-3-(1,1-ethylenedithioethyl)pyridinium bromide 
• 115262-41-4 1-(3-benzyloxy-4-methoxyphenethyl)-3-(1,1-ethylenedioxyethyl)pyridinium bromide 
• 115262-54-9 1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-3-phenylthio-2-piperidone 
• 115262-55-0 3-Benzenesulfinyl-1-[2-(3-benzyloxy-4-methoxy-phenyl)-ethyl]-5-ethyl-piperidin-2-one 
• 115262-57-2 1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-2-oxo-4-piperidinemalonic acid 
• 115288-08-9 1-(3-benzyloxy-4-methoxyphenethyl)-5-(1,1-ethylenedioxyethyl)-2-(1H)-pyridinone 
• 115262-53-8 1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-2-piperidone 
• 115262-56-1 1-(3-benzyloxy-4-methoxyphenethyl)-5-ethyl-5,6-dihydro-2(1H)-pyridinone 
• 115262-49-2 5-acetyl-1-(3-hydroxy-4-methoxyphenethyl)-2-piperidone 
• 115262-36-7 3-benzyloxy-4-methoxyphenethyl bromide 
• 115262-51-6 5-ethyl-1-(3-hydroxy-4-methoxyphenethyl)-2-piperidone 
• 115262-61-8 5-ethyl-1-(3-hydroxyphenethyl)-2-piperidone 

Relevant academic research and scientific papers

PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT

Phellodendrine analogs represented by general formula (I), wherein A represents the group (a); B represents hydrogen, lower alkyl or lower acyl, or alternatively A and B together with the adjacent nitrogen atom form a substituted 1,2,3,4-tetrahydroisoquinoline ring represented by general formula (II), R11, R12, R21, R22, R31 and R32 represent each hydrogen, hydroxyl or lower alkoxy; n1 represents a number of 0 to 2; n2 represents a number of 1 and 2; and m1 represents a number of 0 to 1, provided tsat when A represents the group (b), and n2 is 2, B is lower acyl, and that when A and B together form a substituted 1,2,3,4-tetrahydroisoquinoline ring, n1 is 1 and m1 is not 0. These analogs (I) and related compounds have an excellent activity of suppressing allergy type IV and hence are utilizable as a medicine efficacious against diseases wherein allergy type IV participates, such as chronic hepatitis, intractable asthma, nephrotic syndrome or rheumatism.

Quinolizidines. XXII. An Extension of the "3-Acetylpyridine Route" to the Syntheses of 9-Hydroxy-10-methoxy- and 10-Hydroxy-9-methoxybenzoquinolizidine-Type Alangium Alkaloids

Alternative syntheses of the Alangium alkaloids bearing the 9-hydroxy-10-methoxy- and 10-hydroxy-9-methoxybenzoquinolizidine skeletons (types 3 and 4) have now become feasible through generally applicable routes starting from 3-acetylpyridine.The route