216159-03-4

Basic information

• Product Name: 4-Bromo-2-fluorobenzenesulfonyl chloride
• Synonyms: 2-FLUORO-4-BROMOBENZENESULFONYL CHLORIDE;4-BROMO-2-FLUOROBENZENESULFONYL CHLORIDE;4-BROMO-2-FLUOROBENZENESULPHONYL CHLORIDE;BUTTPARK 147\11-41;4-Bromo-2-fluorobenzenesulphonyl chloride 99%;4-Bromo-2-fluorobenzenesulphonylchloride99%;4-broMo-2-fluorobenzene-1-sulfonyl chloride;4-BroMo-2-fluorobenzenesulfonyl chloride 97%
• CAS NO: 216159-03-4
• Molecular Formula: C6H3BrClFO2S
• Molecular Weight: 273.51
• Product Categories: Fluorobenzene;Aromatic Halides (substituted);Benzenesulfonyl chloride;Benzenes;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Fluorine series
• Mol File: 216159-03-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 63-66 °C(lit.)
• Boiling Point: 84°C 0,5mm
• Flash Point: 84°C/0.5mm
• Appearance: /
• Density: 1.867 g/cm³
• Vapor Pressure: 2.04mmHg at 25°C
• Refractive Index: 1.449
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Toluene
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 4-Bromo-2-fluorobenzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-fluorobenzenesulfonyl chloride(216159-03-4)
• EPA Substance Registry System: 4-Bromo-2-fluorobenzenesulfonyl chloride(216159-03-4)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 22-26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 216159-03-4(Hazardous Substances Data)

Usage

Uses

4-Bromo-2-fluorobenzenesulfonyl chloride may be used to synthesize (E)-4-bromo-2-fluoro-1-styrylbenzene.

General Description

4-Bromo-2-fluorobenzenesulfonyl chloride participates in the generation of tricyclic benzothiadiazepine-1,1-dioxde via pairing reactions with (S)-prolinol.

InChI:InChI=1/C7H3ClF4/c8-2-3-1-4(9)6(11)7(12)5(3)10/h1H,2H2

Upstream product

• 367-24-8 4-bromo-2-fluoroaniline 

Downstream Products

• 1442431-72-2 4-bromo-N-(tert-butyl)-2-(neopentyloxy)benzenesulfonamide 
• 1581710-44-2 4-bromo-N-(1-(ethylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)-2-fluorobenzenesulfonamide 
• 1055995-87-3 4-bromo-N,N-diethyl-2-fluorobenzenesulfonamide 

Relevant articles and documents

NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS

The invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis.

PYRROLO CARBOXAMIDES AS MODULATORS OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (ROR?, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor ROR? and methods for treating ROR? mediated diseases by administrating these novel ROR? modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo carboxamide compounds of Formula (1) and the enantiomers, diastereomers, N-oxides, tautomers, solvates and pharmaceutically acceptable salts thereof.