216174-89-9Relevant academic research and scientific papers
N-silyloxaziridines: Synthesis and use for electrophilic amination
Richy, Nicolas,Ghoraf, Mohammed,Vidal, Jo?lle
, p. 10972 - 10977 (2013/02/22)
N-Silyloxaziridines were synthesized for the first time. Their tert-butyldiphenylsilyl (TBDPS) derivatives were stable reagents that were prepared on a multigram scale in three steps and in 44% overall yield from the corresponding benzylamines. They were mild electrophilic aminating reagents that reacted at room temperature with diversely substituted primary and secondary amines to produce N-monoalkyl or N,N-dialkyl benzaldehyde hydrazones in 44a-87% yield.
