216302-79-3Relevant academic research and scientific papers
Palladium-catalyzed annulation of monosubstituted β-diketones
Buono, Frédéric,Tenaglia, Alphonse
, p. 1153 - 1155 (1998)
Various 4-methylenecyclohexanones and bridged bicyclo[3.n.l]alkanones (n = 2 or 3) are readily available via a palladium-catalyzed C,C-dialkylative cyclisation of monoalkylated β-diketones with allylic diacetate 1a (or dicarbonate 1b). A one-pot bicycloannulation/retro Claisen fragmentation leading to medium-sized cycloalkanones from monoalkylated cyclic β-diketones is described.
