216305-79-2Relevant academic research and scientific papers
Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase
Velázquez, Sonsoles,Chamorro, Cristina,Pérez-Pérez, María-Jesús,Alvarez, Rosa,Jimeno, Maria-Luisa,Martín-Domenech, Angel,Pérez, Carlos,Gago, Federico,De Clercq, Erik,Balzarini, Jan,San-Félix, Ana,Camarasa, María-José
, p. 4636 - 4647 (2007/10/03)
With the aim of assessing the role that the thymine base of TSAO-T may play in the interaction of TSAO compounds with HIV-1 reverse transcriptase (RT), we have designed, synthesized, and evaluated for their anti-HIV-1 activity a series of 3-spiro sugar de
