216312-53-7Relevant academic research and scientific papers
Lactam glycogen phosphorylase inhibitors and method of use
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Page/Page column 39, (2010/02/05)
A compound of formula I wherein W is a bicyclic hetroaryl of the structure X is —O—, —S—, —SO2—, —CHR5—, —CHR5O—, —CHR5S—, —CHR5SO2—, —CHR5CO— or —CH2CHR5—;
A versatile synthesis of 2-substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepine-3-ones
Van Rompaey, Karolien,Van Den Eynde, Isabelle,De Kimpe, Norbert,Tourwé, Dirk
, p. 4421 - 4432 (2007/10/03)
A mild and general strategy for the synthesis of 2-substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepine-3-ones is described. The seven-membered lactam is prepared by intramolecular amide bond formation from the intermediate amino acid, which is obtained e
