216314-06-6Relevant academic research and scientific papers
Utilization of the inherent nucleophile for regioselective O-acylation of polyphenols via an intermolecular cooperative transesterification
Liu, Jingchao,Fu, Junjie,Li, Wenlong,Zou, Yu,Huang, Zhangjian,Xu, Jinyi,Peng, Sixun,Zhang, Yihua
, p. 4103 - 4110 (2016/07/06)
A green and efficient method for regioselective O-acylation of polyphenols has been developed. The acylation can be carried out in potassium carbonate/dimethyl sulphoxide system by utilizing the ‘inherent nucleophile’ via an intermolecular cooperative transesterification under mild condition. This method shows particular advantage in regioselective acylation of polyphenols bearing 2′,4′-dihydroxyacetophenone moiety and can be extended to the synthesis of mono or multiple acetates of polyphenols without this moiety in good yields. Compared with other reported approaches, this method is endowed with atom economy and is more environment-friendly for avoiding the use of any metal-based catalysts.
2,3-dihydrobenzofuran derivatives
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, (2008/06/13)
2,3-Dihydrobenzofuran derivatives of general formula (1): wherein R1represents a hydrogen atom or an acyl group; R2, R3and R4represent a hydrogen atom, a lower alkyl group or a lower alkenyl group; R5
