216569-15-2

Basic information

• Product Name: (5R)-4-Benzyl-5-phenyl[1,3,4]oxadiazinan-2-one
• Synonyms: (5R)-4-Benzyl-5-phenyl[1,3,4]oxadiazinan-2-one
• CAS NO: 216569-15-2
• Molecular Weight: 268.315
• Mol File: 216569-15-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5R)-4-Benzyl-5-phenyl[1,3,4]oxadiazinan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-4-Benzyl-5-phenyl[1,3,4]oxadiazinan-2-one(216569-15-2)
• EPA Substance Registry System: (5R)-4-Benzyl-5-phenyl[1,3,4]oxadiazinan-2-one(216569-15-2)

Safety Data

• Hazardous Substances Data: 216569-15-2(Hazardous Substances Data)

Upstream product

• 64269-79-0 Carbonyldiimidazole 
• 216569-14-1 (2R)-2-(N-Benzylhydrazino)-2-phenylethanol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 216569-13-0 (2R)-2-(N-Benzylnitrosoamino)-2-phenylethanol 
• 14231-57-3 (R)-N-benzyl-2-phenylglycinol 

Downstream Products

• 226970-74-7 (4R,6R,7S,8R)-1-Oxo-4,6-diphenyltetrahydropyrazolo[1,2-c][1,3,4]oxadiazine-7,8-dicarboxylic acid dimethyl ester 
• 226970-66-7 (2R)-1-(2-Hydroxy-1-phenylethyl)-5-phenyl-1H-pyrazole-3,4-dicarboxylic acid diethyl ester 
• 226970-62-3 (4R,6S)-1-Oxo-4,6-diphenyl-3,4-dihydro-6H-pyrazolo[1,2-c][1,3,4]oxadiazine-7,8-dicarboxylic acid diethyl ester 
• 298213-97-5 (1R,3S,7R)-7-Phenyl-1,3-dipropyldihydro-2,5-dioxa-3a,7a-diazainden-4-one 
• 298213-92-0 (4R,6S,7S,8R)-1-Oxo-4-phenyl-6-propyltetrahydropyrazolo[1,2-c][1,3,4]oxadiazine-7,8-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Diastereoselective cycloadditions of chiral non-racemic azomethine imines

(5R)-5-Phenyl[1,3,4]oxadiazinan-2-one (6) is an easily available building block and acts as a chiral non-racemic precursor for azomethine imines. The ylid can be formed regioselectively with various aldehydes and reacts in an efficient manner with a wide range of dipolarophiles. The regio- and diastereoselectivity of the cycloadditions have been fully investigated and can lead, in the best cases, to the creation of three contiguous asymmetric centers in a single step, with complete control of relative and absolute configurations.