216668-01-8

Upstream product

• 216667-19-5 (R)-1-(o-methoxyphenylmethyl)-3-hydroxypyrrolidine 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 216667-56-0 (S)-1-((o-methoxyphenyl)methyl)-3-azidopyrrolidine 

Relevant academic research and scientific papers

2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

Structure-selectivity relationship in alkyllithium-aldehyde condensations using 3-aminopyrrolidine lithium amides as chiral auxiliaries

A nonracemizing route to a set of chiral 3-aminopyrrolidines, based on 4-hydroxy-(L)-proline, is described. The induction potential of the lithium amides derived from these diamines has then been investigated in the asymmetric addition of alkyllithium com