216669-64-6

Upstream product

• 851889-69-5 (E)-(5S,6S,7R,8R,9S)-6,8,10-Trihydroxy-5,7,9-trimethyl-dec-3-enoic acid methyl ester 
• 184528-55-0 (3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester 
• 184528-54-9 (3E,5R,6S,7S)-6,8-dihydroxy-5,7-dimethyloct-3-enoic acid methyl ester 
• 184758-35-8 (3E,5S,6S,7R,8R,9S)-(E)-8,10-O-[bis-(1,1-dimethylethyl)silylene]-6-hydroxy-5,7,9-trimethyldec-3-enoic acid methyl ester 
• 184528-56-1 (2S,3R,4S)-3,5-O-[bis-(1,1-dimethylethyl)silylene]-2,4-dimethylpropionaldehyde 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 851889-72-0 (3R,4S,5S,6S,7S)-7-[(2R,4R,5S)-2-(4-Methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-5-methyl-6-triethylsilanyloxy-3-trimethylsilanyl-oct-1-en-4-ol 
• 851889-71-9 (E)-(5S,6S,7S)-7-[(2R,4R,5S)-2-(4-Methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-5-methyl-6-triethylsilanyloxy-oct-3-enoic acid methyl ester 
• 216670-83-6 (2R,3R,4S)-4-[(2R,4R,5S)-2-(4-Methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-2-methyl-3-triethylsilanyloxy-pentanal 
• 851889-70-8 (3E,5S,6S,7R,8R,9S)-6-hydroxy-8,10-[(R)-4-methoxybenzilidenedioxy]-5,7,9-trimethyldec-3-enoic acid methyl ester 
• 216669-57-7 (2S,3R,4R,5S,6S,7Z)-5-triethylsilanyloxy-1,3-[(R)-4-methoxybenzilidenedioxy]-2,4,6-trimethyldeca-7,9-diene 

Downstream Products

• 216669-69-1 (2R,3S,4S,5S,6S,7Z)-1-iodo-3-(4-methoxybenzyloxy)-2,4,6-trimethyl-5-triethylsilanyloxydeca-7,9-diene 
• 851889-87-7 (R)-2-[(2S,4S,5S,6S)-6-((3Z,8Z,16Z)-(2S,5S,6S,7S,11S,12R,13S,14S,15S)-14-Carbamoyloxy-12-hydroxy-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8,16,18-tetraenyl)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-86-6 (2R,3S,4S,5S,7S,8Z,10S,11S,12S,13Z,16S,17R,18S,19S,20S,21Z)-19-hydroxy-3,5-[(S)-4-methoxybenzilidenedioxy]-7,11-bis-methoxymethoxy-17-(4-methoxyphenoxyphenoxy)-2,4,10,12,14,16,18,20-octamethyltetracosa-8,13,21,23-tetraenoic acid methyl ester 
• 851889-65-1 2-[6-[14-carbamoyloxy-12-(4-methoxy-benzyloxy)-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8,16,18-tetraenyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-85-5 2-[6-[12-(4-methoxy-benzyloxy)-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-14-triethylsilanyloxy-nonadeca-3,8,16,18-tetraenyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Crotylsilane reagents in the synthesis of complex polyketide natural products: Total synthesis of (+)-discodermolide

An efficient, highly convergent stereocontrolled synthesis of (+)-discodermolide has been achieved with 2.1% overall yield (27 steps longest linear sequence). The absolute stereochemistry of the C1-C6 (12), C7-C14 (13), and C15-C24 (11) subunits was intro