216755-56-5

Basic information

• Product Name: 3-BROMO-5-FLUOROBENZYL ALCOHOL
• Synonyms: 3-BROMO-5-FLUOROBENZYL ALCOHOL;3-Bromo-5-fluorobenzyl alcohol 98%;3-Bromo-5-fluorobenzylalcohol98%;(3-BroMo-5-fluorophenyl)Methanol;(3-Bromo-5-fluorophenyl)
• CAS NO: 216755-56-5
• Molecular Formula: C₇H₆BrFO
• Molecular Weight: 205.02
• Product Categories: Alcohol;Alcohols;Bromine Compounds;Fluorine Compounds
• Mol File: 216755-56-5.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 259 °C at 760 mmHg
• Flash Point: 110.5 °C
• Appearance: Colorless/Liquid
• Density: 1.658 g/cm³
• Vapor Pressure: 1.44mmHg at 25°C
• Refractive Index: 1.427
• PKA: 13.94±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-5-FLUOROBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-FLUOROBENZYL ALCOHOL(216755-56-5)
• EPA Substance Registry System: 3-BROMO-5-FLUOROBENZYL ALCOHOL(216755-56-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 216755-56-5(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-fluorobenzyl alcohol is a chemical compound with the molecular formula C7H6BrFO. It is an organic compound that contains a benzyl alcohol group, a bromine atom, and a fluorine atom, making it a derivative of benzyl alcohol. It is commonly used as a reagent in organic synthesis, and its properties make it a valuable intermediate in the production of pharmaceuticals and agrochemicals. The compound has a wide range of applications in the chemical industry and is known for its ability to undergo various chemical reactions, making it useful in the synthesis of diverse organic compounds.

InChI:InChI=1/C7H6F3NO/c1-12-5-2-3-6(11-4-5)7(8,9)10/h2-4H,1H3

Upstream product

• 433939-27-6 3-bromo-5-fluorophenol 
• 188813-02-7 3-bromo-5-fluorobenzaldehyde 
• 176548-70-2 3-bromo-5-fluorobenzoic acid 

Downstream Products

• 305800-58-2 2-[3-bromo-5-fluorophenyl]acetonitrile 
• 761424-41-3 [(3-bromo-5-fluorobenzyl)oxy] (tert-butyl)diphenylsilane 

Relevant articles and documents

AZOLE-SUBSTITUTED PYRIDINE COMPOUND

The present invention provides a compound represented by formula [I'| shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme, wherein the structure represented by formula [III] shown below represents any of the structures represented by formula group [IV] shown below, wherein R1 represents a hydrogen atom, a fluorine atom, methyl, etc.; R2, R3, and R4 each independently represent a hydrogen atom, a fluorine atom, or methyl; W represents a single bond, C1-3alkanediyl, or the formula -O-CH2CH2-; and ring A represents (a) substituted C4-6cycloalkyl, (b) substituted 4- to 6-membered saturated nitrogen-containing heterocyclyl, (c) substituted phenyl, (d) substituted pyridyl, (e) substituted 2,3-dihydrobenzofuran, (f) 4- to 6-membered saturated oxygen-containing heterocyclyl, etc.

SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS

The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating bone remodeling, for stimulating the differentiation and mineralization of osteoblasts, for inhibiting bone resorption and for modulating serum level of adiponectin in a subject. These uses have been found for compounds represented by Formula I and pharmaceutically acceptable salts thereof. wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)-(CH2)n-CH3 or CH(OH)-(CH2)n-CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is H, F, OH, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)-(CH2)n-CH3 or CH(OH)-(CH2)n-CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, F, or OH; Q is 1) (CH2)mC(O)OH wherein m is 1 or 2, 2) CH(F)-C(O)OH, 3) CF2-C(O)OH or 4) C(O)-C(O)OH.

Aminoheteroaryl benzamides as kinase inhibitors

The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.