21676-06-2

Upstream product

• 21676-03-9 (Z)-3-hexenyl iodide 
• 603-35-0 triphenylphosphine 
• 1002-28-4 3-hexyn-1-ol 
• 102998-71-0 4-iodo-1-ethylbut-1-yne 
• 34019-85-7 (Z)-3-hexenyl-1-tosylate 
• 928-96-1 (Z)-3-Hexen-1-ol 

Downstream Products

• 467217-02-3 tert-Butyl-[(3Z,6Z)-1-(3-dimethoxymethyl-phenyl)-nona-3,6-dienyloxy]-diphenyl-silane 
• 1434154-50-3 (R,E)-methyl 7-((tert-butyldiphenylsilyl)oxy)-9-((2R,3S,5R)-3-((tert-butyldiphenylsilyl)oxy)-5-((S,3Z,6Z)-1-((tertbutyldiphenylsilyl)oxy)nona-3,6-dien-1-yl)tetrahydrofuran-2-yl)non-8-en-4-ynoate 
• 102692-73-9 7β-(5-benzyloxypentyl)-2β-<3α-(tetrahydropyran-2-yl)oxy-1(E),5(Z)-octadienyl>-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 102692-73-9 C₃₈H₅₈O₅ 
• 102692-76-2 7β-(5-benzyloxypentyl)-2β-(3β-hydroxy-1(E),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 102692-76-2 7β-(5-benzyloxypentyl)-2β-(3α-hydroxy-1(E),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 102692-72-8 7β-(5-benzyloxypentyl)-2β-(3-oxo-1(E),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 71846-42-9 (+/-)-6,9α-methanoprostaglandin I3 
• 71846-42-9 6,9a-methanoprostaglandin I₃ 
• 102692-71-7 7β-(5-benzyloxypentyl)-2β-(1α-phenylthio-2(Z),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 102692-71-7 7β-(5-benzyloxypentyl)-2β-(1β-phenylthio-2(Z),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)-oxybicyclo<3.3.0>octane 
• 89408-55-9 7,7-ethylenedioxy-2β-(1β-phenylthio-2(Z),5(Z)-octadienyl)-3α-(tetrahydropyran-2-yl)oxybicyclo<3.3.0>octane 

Relevant academic research and scientific papers

Practical synthesis of (9S,10R)-9,10-epoxy-(3Z,6Z)-henicosadiene: The major pheromone of the saltmarsh caterpillar moth Estigmene acrea

An efficient synthesis of (3Z,6Z)-cis-9,10-epoxy-3,6-henicosadiene (1), the major component of sex pheromone of saltmarsh caterpillar moth Estigmene acrea (Drury), was accomplished from commercially available pentadec-3-yn-1-ol and bromoundecane. Chiralit

The first total synthesis of iPF4α-VI and its deuterated analog

The total and stereospecific syntheses of iPF4α-VI and d4-iPF4α-VI have been accomplished. iPF4α-VI is a docosahexanenoic acid (DHA)-derived isoprostane. DHA is the most abundant polyunsaturated fatty acid in the brain. Different synthetic designs have been used for the two syntheses. In the d4-iPF4α-VI design, the deuterated part of the molecule was introduced last in the synthesis.

Total synthesis of isoprostanes derived from adrenic acid and EPA

Enantiomerically enriched F2-dihomo-isoprostanes and F 3-isoprostanes have been synthesized. Such compounds are derived from the action of reactive oxygen species on the phospholipid-bound polyunsaturated fatty acids (PUFA), adrenic