21677-65-6 Usage
Amino alcohol derivative
It is a compound that contains both an amino group (-NH2) and a hydroxyl group (-OH) in its structure.
Nitroimidazole group
A functional group present in the compound, which consists of an imidazole ring with a nitro group (-NO2) attached to it. This group is responsible for its radiosensitizing properties.
Radiosensitizer
2-[(1,2-dimethyl-4-nitro-1H-imidazol-5-yl)amino]ethanol is used to increase the sensitivity of tumor cells to radiation, leading to better therapeutic outcomes in cancer treatment.
Enhances radiation therapy effectiveness
The compound has been found to improve the effectiveness of radiation therapy by increasing the sensitivity of tumor cells to radiation.
Induces DNA damage
It exerts its radiosensitizing effect by causing DNA damage in cancer cells, making them more susceptible to the cytotoxic effects of radiation.
Inhibits repair mechanisms
The compound also inhibits the repair mechanisms in cancer cells, preventing them from fixing the DNA damage caused by radiation.
Check Digit Verification of cas no
The CAS Registry Mumber 21677-65-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,7 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 21677-65:
(7*2)+(6*1)+(5*6)+(4*7)+(3*7)+(2*6)+(1*5)=116
116 % 10 = 6
So 21677-65-6 is a valid CAS Registry Number.
21677-65-6Relevant academic research and scientific papers
Kochergin,Reznichenko,Gireva,Aleksandrova
, p. 1142 - 1147 (1998)
A series of 1-alkyl(1,2-dialkyl)-substituted 4-nitro-5-hydroxyalkylamino- and 4-hydroxyalkylamino-5-nitroimidazoles were obtained by the reaction of 1-alkyl(1,2-dialkyl)-substituted 4-nitro-5-chloro(bromo)imidazoles with amino alcohols. Their reactions wi
