Used as an antineoplastic
phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase
DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription
A STAT-1 activation inhibitor and a DNA synthesis inhibitor.?
Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo .
Irreversible muscarinic agonist