2168-96-9

Basic information

• Product Name: DI-N-DODECYL SULFOXIDE
• Synonyms: DODECYL SULFOXIDE;DIDODECYL SULFOXIDE;DI-N-DODECYL SULFOXIDE;N-DODECYL SULFOXIDE;1,1'-sulphinylbisdodecane;1-dodecylsulfinyldodecane;1-laurylsulfinyldodecane
• CAS NO: 2168-96-9
• Molecular Formula: C₂₄H₅₀OS
• Molecular Weight: 386.72
• EINECS: 218-513-5
• Mol File: 2168-96-9.mol
• Article Data: 33

Chemical Properties

• Melting Point: 91 °C
• Boiling Point: 505.1 °C at 760 mmHg
• Flash Point: 259.3 °C
• Appearance: /
• Density: 0.89 g/cm³
• Solubility: soluble in dichloromethane
• CAS DataBase Reference: DI-N-DODECYL SULFOXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DI-N-DODECYL SULFOXIDE(2168-96-9)
• EPA Substance Registry System: DI-N-DODECYL SULFOXIDE(2168-96-9)

Safety Data

• Hazardous Substances Data: 2168-96-9(Hazardous Substances Data)

Usage

General Description

DI-N-DODECYL SULFOXIDE is a chemical compound with the molecular formula C24H50SO2. It is commonly used as a surfactant and detergent in various industrial and household cleaning products. This chemical is known for its ability to lower the surface tension of liquids, making it an effective ingredient in formulations for cleaning and emulsifying oils and greases. It is also used as a wetting agent in pesticide formulations and as a solvent in chemical reactions. DI-N-DODECYL SULFOXIDE is considered to be relatively low in toxicity and is generally regarded as safe for use in the intended applications when handled and used as directed.

Upstream product

• 2469-45-6 didodecyl sulfide 
• 112-55-0 1-dodecylthiol 
• 143-15-7 1-dodecylbromide 
• 1233477-18-3 C₁₉H₂₆N₂O₁₁Se 

Downstream Products

• 112-40-3 dodecane 
• 2469-45-6 didodecyl sulfide 

Relevant articles and documents

Green synthesis of gold nanoparticles (Au NPs) using Tribulus terrestris extract: Investigation of its catalytic activity in the oxidation of sulfides to sulfoxides and study of its anti-acute leukemia activity

With regards to applied, facile, green chemical research, a bio-inspired approach is being reported for the synthesis of Au NPs by using Tribulus terrestris extract. The innate oxygenated phytochemicals facilitated the green reduction of Au3+ ions to corresponding NPs and also stabilized them by encapsulating them. This modification prevented the as-synthesized Au NPs towards agglomeration and tiny NPs were obtained in uniformly spherical in shape and in the range of 10–15 nm dimension. Physicochemical characteristics of the green synthesized Au NPs were evaluated by advanced physicochemical techniques like UV–Vis and FT-IR spectroscopy, SEM, TEM, EDX and XRD study. Catalytic performance of the biomolecule functionalized Au NPs was investigated in the controlled and selective oxidation of sulfides to sulfoxides using hydrogen peroxide as green oxidant at room temperature. Aromatic, aliphatic and heterocyclic sulfides were oxidized to their corresponding sulfoxides with high yields without formation of over oxidized sulfones. The catalyst was easily recovered and recycled for 8 successive times without noticeable decrease in catalytic activity. In addition, the biosynthesized Au NPs indicated suitable antioxidant and anti-acute leukemia properties against THP-1 cell line. Tribulus terrestris extract and the green synthesized Au NPs exhibited a maximum DPPH scavenging activity of 78% and 29.37%, respectively. Again, in the anticancer studies over THP-1 cell line following MTT assay, the Au NP exhibited gradual reduced % cell viability with increase in its concentration. At an Au NPs concentration of 2000 μg/mL, the % toxicity became maximum suggesting efficient inhibition of cancer invasion. Based on the above results, Au NPs-Tribulus could be administered as a potential anti-leukemia drug for the treatment of acute leukemia following the clinical trial studies in humans.

Applications of iron and nickel immobilized on hydroxyapatite-core-shell γ-Fe2O3 as a nanomagnetic catalyst for the chemoselective oxidation of sulfides to sulfoxides under solvent-free conditions

In the present study, Fe2+ and Ni2+ immobilized on hydroxyapatite-core-shell γ-Fe2O3 (γ-Fe2O3@HAp-Fe2+ and γ-Fe2O3@HAp-Ni2+) with a high surface area has been synthesized and characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), transmission electron microscopy (TEM), and scanning electron microscope (SEM) techniques. Then, γ-Fe2O3@HAp-Fe2+ and γ-Fe2O3@HAp-Ni2+ were used as a new and magnetically recoverable nano catalyst for the selective oxidation of sulfides to sulfoxides with 33% aqueous H2O2 (0.5 mL) as an oxidant at room temperature in good to excellent yields and short reaction time. Nontoxicity of reagent, mild reaction condition, inexpensive and high catalytic activity, simple experimental procedure, short period of conversion and excellent yields, and ease of recovery from the reaction mixture using an external magnet are the advantages of the present method.

Laccase-TEMPO as an efficient catalyst system for metal- and halogen-free aerobic oxidation of thioethers to sulfoxides in aqueous media at ambient conditions

We present for the first time an eco-friendly procedure for the aerobic oxidation of thioethers to sulfoxides using laccase-TEMPO catalyst system. This catalyst system allows for simpler (easy work-up) and greener methodologies (room temperature, phosphate buffer) while keeping high reaction yields and selectivity. This work is superior to others due to free from any transition metal and halide co-catalysts.