21690-60-8Relevant academic research and scientific papers
Synthesis method of 3-ethoxy-N-p-tolyl propionamide
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Paragraph 0020-0053, (2020/06/05)
The invention relates to the technical field of fine chemical engineering, and discloses a synthetic method of 3-ethoxy-N-p-tolyl propionamide. The preparation method comprises the specific steps: adding N-p-tolyl acrylamide, potassium fluoride and a metal oxide catalyst into a certain amount of ethanol, and heating and stirring to react, and thus obtaining 3-ethoxy-N-p-tolyl propionamide. Compared with an existing synthesis method, the method does not need to introduce a strong acid or strong alkali reagent, has the advantages of high yield, simple operation and small influence on the environment, has potential industrial value, and is worthy of popularization and application.
Efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base
Wang, Feng,Yang, Haijun,Fu, Hua,Pei, Zhichao
supporting information, p. 517 - 519 (2013/02/23)
A novel and efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base has been developed. The protocol uses readily available acrylic derivatives and primary alcohols as the starting materials, inexpensive CuCl2 as the catalyst, and the corresponding addition products were obtained in moderate to excellent yields.
