217180-11-5Relevant articles and documents
Total synthesis of bleomycin group antibiotics. Total syntheses of bleomycin demethyl A2, bleomycin A2, and decarbamoyl bleomycin demethyl A2
Katano, Kiyoaki,An, Haoyun,Aoyagi, Yoshiaki,Overhand, Mark,Sucheck, Steven J.,Stevens Jr., William C.,Hess, Cynthia D.,Zhou, Xiang,Hecht, Sidney M.
, p. 11285 - 11296 (2007/10/03)
The total syntheses of bleomycin A2 (1) by two routes are described. The final step in the synthesis of bleomycin A2 involves methylation of bleomycin demethyl A2 (2). This bleomycin derivative is of interest mechanistical