217186-60-2Relevant academic research and scientific papers
HETEROCYCLIC THIOESTER AND KETONE HAIR GROWTH COMPOSITIONS AND USES
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Page/Page column 18, (2010/11/23)
This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
Synthesis of ketone analogues of prolyl and pipecolyl ester FKBP12 ligands
Wu, Yong-Qian,Wilkinson, Douglas E.,Limburg, David,Li, Jia-He,Sauer, Hansjorg,Ross, Doug,Liang, Shi,Spicer, Dawn,Valentine, Heather,Fuller, Mike,Guo, Hong,Howorth, Pam,Soni, Raj,Chen, Yi,Steiner, Joseph P.,Hamilton, Gregory S.
, p. 3558 - 3568 (2007/10/03)
The recently discovered small-molecule ligands for the peptidyl and prolyl isomerases (PPIase) of FKBP12 have been shown to possess powerful neuroprotective and neuroregenerative effects. Ketone analogues of the prolyl and pipecolyl esters, which mimic on
