2172-44-3Relevant academic research and scientific papers
Dual off-on and on-off fluorescent detection of Zn2+/Cd 2+ ions based on carbazolone substituted 2-aminobenzamides
Xu, Qin-Chao,Zhu, Xue-Hui,Jin, Can,Xing, Guo-Wen,Zhang, Yuan
, p. 3591 - 3596 (2014)
Two new 2-aminobenzamide structural isomers, 4-isoACOBA and 5-isoACOBA, as fluorescent probes for Cd2+ and Zn2+ were fabricated with carbazolone as fluorophore and N,N-bis(2-pyridylmethyl)ethylenediamine (BPEA) as chelator. With Cd2+/Zn2+ as input, the two probes are characteristic of the transformation from "off-on" to "on-off" molecular switch by interchanging the substitution position of the fluorophore from C-4 to C-5 at the benzene ring. 4-IsoACOBA is a Cd 2+-specific turn-on fluorescent probe exhibiting good discrimination between Cd2+ and Zn2+ with FCd2+/F Zn2+ = 2.48, while 5-isoACOBA is a Zn2+-specific turn-off probe with FCd2+/FZn2+ = 4.50. The binding behaviours of 4-isoACOBA-Cd(ii) and 5-isoACOBA-Zn(ii) were deeply investigated by UV and fluorescence titration, ESI-MS analysis, and DFT study. The results indicate that both the electron donating/withdrawing ability and the substituted position of the fluorophore have remarkable influences on the probe sensing properties and selectivity.
An easy access to carbazolones and 2,3-disubstituted indoles
Janreddy, Donala,Kavala, Veerababurao,Bosco, J. W. John,Kuo, Chun-Wei,Yao, Ching-Fa
scheme or table, p. 2360 - 2365 (2011/06/16)
Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes. Copyright
