21721-08-4

Basic information

• Product Name: Mammea A/AB cyclo F
• Synonyms: 4-Phenyl-5-hydroxy-6-(2-methylpropionyl)-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one;5-Hydroxy-8,8-dimethyl-6-(2-methyl-1-oxopropyl)-4-phenyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one;Mammea A/AB cyclo F;Mesuagin
• CAS NO: 21721-08-4
• Molecular Formula: C₂₄H₂₂O₅
• Molecular Weight: 390.42848
• Mol File: 21721-08-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Mammea A/AB cyclo F(CAS DataBase Reference)
• NIST Chemistry Reference: Mammea A/AB cyclo F(21721-08-4)
• EPA Substance Registry System: Mammea A/AB cyclo F(21721-08-4)

Safety Data

• Hazardous Substances Data: 21721-08-4(Hazardous Substances Data)

Upstream product

• 16981-20-7 5,7-dihydroxy-6-isobutyryl-8-(3-methylbut-2-enyl)-4-phenyl-2H-chromen-2-one 

Relevant articles and documents

4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials

Supercritical CO2 selectively extracted a series of 4-alkyl and 4-phenyl 5,7-dihydroxycoumarins from Mesua ferrea blossoms. Chemical modifications of the isolated compounds allowed us to confirm the structures elucidated by spectroscopic means and to prepare new derivatives amenable to SAR studies and potential pharmaceutical development. Biological investigations towards the screening on a number of bacteria strains and Plasmodium falciparum, identified compounds 1-9 as weak antiprotozoal agents and potent antibacterials on resistant Gram-positive strains.