217312-71-5Relevant academic research and scientific papers
Grignard reagent/CuI/LiCl-mediated stereoselective cascade addition/cyclization of diynes: A novel pathway for the construction of 1-methyleneindene derivatives
Li, De-Yao,Wei, Yin,Shi, Min
, p. 15682 - 15688 (2013)
Diynes containing a cyclopropane group smoothly undergo a novel intramolecular and stereoselective cascade addition/cyclization reaction to produce the corresponding 1-methyleneindene derivatives in moderate to good yields. This interesting transformation is mediated by Grignard reagent/CuI with LiCl as an additive under mild conditions. The obtained product can easily be further functionalized through cyclopropyl ring opening. A plausible reaction mechanism has also been presented on the basis of deuterium labeling and control experiments. Diyne cyclization: Diynes containing a cyclopropane group undergo a novel intramolecular and stereoselective cascade addition/cyclization reaction to produce the corresponding 1-methyleneindene derivatives (see scheme). The transformation proceeds under mild conditions and is promoted by a combination of Grignard reagent Copyright
The Gold(I)-Mediated Domino Reaction to Fused Diphenyl Phosphoniumfluorenes: Mechanistic Consequences for Gold-Catalyzed Hydroarylations and Application in Solar Cells
Arndt, Sebastian,Borstelmann, Jan,Eshagh Saatlo, Rebeka,Antoni, Patrick W.,Rominger, Frank,Rudolph, Matthias,An, Qingzhi,Vaynzof, Yana,Hashmi, A. Stephen K.
, p. 7882 - 7889 (2018/06/15)
A domino sequence, involving a phosphinoauration and a gold-catalyzed 6-endo-dig cyclization step, was developed. Starting from modular and simple-to-prepare phosphadiynes, π-extended phosphoniumfluorenes were synthesized. The mechanistic proposal was sup
Simple gold-catalyzed synthesis of benzofulvenes-gem-Diaurated species as "instant dual-activation" precatalysts
Hashmi, A. Stephen K.,Braun, Ingo,Noesel, Pascal,Schaedlich, Johannes,Wieteck, Marcel,Rudolph, Matthias,Rominger, Frank
, p. 4456 - 4460 (2012/06/04)
Alkyl-substituted diynes deliver benzofulvenes in a unique gold-catalyzed reaction. The catalytic cycle involves the formation of gold acetylides by alkynyl C-H activation, the formation of vinylidene gold(I) intermediates by dual activation, and alkyl C-H activation by the vinylidene gold(I) species. gem-Diaurated species obtained from the catalysis reactions prove to be highly active catalysts for these conversions. Copyright
Cyclization of carbonyl substituted enyne-allenes: C2-C6-cyclization induced by heat or by addition of samarium(II) iodide, samarium(III) chloride, or boron trifluoride
Schmittel, Michael,Strittmatter, Marc
, p. 13751 - 13760 (2007/10/03)
Under a variety of conditions the reaction of enyne-allenes with carbonyl substituents at the allene and phenyl or t-butyl groups at the alkyne terminus afforded products via the new C2-C6-cyclization. Products of the Myers-Saito-cyc
