217322-53-7Relevant academic research and scientific papers
Lipase-catalyzed kinetic resolution of the racemic mixtures of 1- aryloxy-3-nitrato-and-1-aryloxy-3-azido-2-propanols
Pchelka, Beata,Radomska, Justyna,Plenkiewicz, Jan
, p. 4355 - 4364 (1998)
The racemic mixtures of 1-aryloxy-3-nitrato-2-propanols and 1-aryloxy- 3-azido-2-propanols were resolved with moderate selectivity by the lipase- mediated acylation with vinyl acetate. The effects of the nature, position, and spatial requirements of the p
Efficient regio- and stereoselective conversions of oxiranes and aziridines into β-(nitrooxy)-substituted alcohols and amines by using bismuth nitrate
Das, Biswanath,Krishnaiah, Maddeboina,Venkateswarlu, Katta,Reddy, Vtukuri Saidi
, p. 110 - 113 (2007/10/03)
Oxiranes and aziridines efficiently undergo ring opening with bismuth nitrate at room temperature to furnish the corresponding β-(nitrooxy)- substituted alcohols and amines respectively. The conversions are highly regio- and stereoselective and afford the
Zirconyl nitrate mediated regioselective ring opening of epoxides and aziridines: an easy synthesis of β-nitrato-alcohols and -sulfonamides
Das, Biswanath,Krishnaiah, Maddeboina,Venkateswarlu, Katta
, p. 6027 - 6029 (2007/10/03)
Epoxides and aziridines are cleaved efficiently and regioselectively in the presence of zirconyl nitrate at room temperature to afford the corresponding β-nitrato-alcohols and -sulfonamides, respectively, in high yields.
Resolution of racemic 3-aryloxy-1-nitrooxypropan-2-ols by lipase-catalyzed enantioselective acetylation
Pchelka, Beata Krystyna,Loupy, Andre,Plenkiewicz, Jan,Petit, Alain,Blanco, Luis
, p. 2109 - 2119 (2007/10/03)
Both (R)- and (S)-enantiomers of 3-aryloxy-1-nitrooxypropan-2-ols (R)-(-)-1, (S)-(+)-2 were prepared in high enantiomeric excess by lipase from Pseudomonas cepacia (Amano PS) or Pseudomonas fluorescens (Amano AK)-catalyzed acetylation of racemic alcohols 1a-g with vinyl acetate in n-hexane at 4 or 22°C. The enantioselectivity of this transformation was dependent on the substitution pattern of the aryl ring with E-values ranging from 31 to 111.
